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Office of Interactive E-Learning
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University of Nebraska Medical Center

Tag: renal

Cisplatin, Fanconi Syndrome, Pharmacology, proximal tubule, renal

Cisplatin and Fanconi Syndrome

In this module, you will learn how cisplatin functions as a potent chemotherapeutic agent and examine its renal handling, focusing on the transporters involved in proximal tubule secretion. You will also investigate how certain drug interactions may worsen kidney injury and connect the clinical presentation of Fanconi Syndrome with its underlying pathophysiology.

Feb 10, 2025

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Angiotensin II, GFR, glomerular filtration rate, RAAS, renal, Renal Artery Stenosis, Renin Angiotensin Aldosterone System

Renin-Angiotensin-Aldosterone System (RAAS) & Renal Artery Stenosis

This module begins by exploring how the renin-angiotensin-aldosterone system (RAAS) maintains homeostasis by preventing a decrease in glomerular filtration rate (GFR) during periods of low blood pressure. It then examines the role of angiotensin II as the key effector in preserving GFR throughout the body. Finally, the module addresses renal artery stenosis, a condition in […]

Nov 19, 2024

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aldosterone switch, distal nephron physiology, familial hypokalemia-hypomagnesemia, Gitelman syndrome, Gordon syndrome, high potassium, low volume, pseudohypoaldosteronism, renal

Low Volume High Potassium Aldosterone Switch

The module begins with an overview of the relevant renal physiology, focusing on the mechanisms of sodium and potassium handling. It then examines how low extracellular fluid volume and high potassium levels influence reabsorption processes at the distal nephron. Finally, these physiological mechanisms are clinically correlated with Gordon syndrome and Gitelman syndrome, highlighting their pathophysiology […]

Nov 18, 2024

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Diuretic, Electrolyte, kidney, Loop, Nephrology, Pharmacology, renal, Thiazide

Diuretics

This e-module uses animations, interactive tables, and practice questions with explanations to reinforce understanding of diuretic medications.  The module provides information on renal physiology, diuretic mechanisms, diuretic indications, and drug side effects.

Apr 3, 2023

Diabetes, gluclose, kidney, renal, SGLT2

Renal Physiology and the Action of SGLT2 Inhibitors

In this module, you will first learn about autoregulation of renal blood flow and the normal physiology of tubular glucose reabsorption. We will then move on to cover renal pathology in diabetes. We will finish with the treatment of diabetes using SGLT2 inhibitors.

Dec 9, 2021

case study, Diagnosis, kidney, Pathology, renal, Renal Pathology, tumor

Kidney Tumors

In this E-module, 10 cases are used to illustrate some of the different pathologies of kidney tumors. This module is designed for M2 students and Pathology residents.

Aug 26, 2020