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University of Nebraska Medical Center

Low Volume High Potassium Aldosterone Switch

Module Screenshot

The module begins with an overview of the relevant renal physiology, focusing on the mechanisms of sodium and potassium handling. It then examines how low extracellular fluid volume and high potassium levels influence reabsorption processes at the distal nephron. Finally, these physiological mechanisms are clinically correlated with Gordon syndrome and Gitelman syndrome, highlighting their pathophysiology and clinical implications.

Format: E-Learning Module
Development Date: November 18, 2024
Authors: Steven Sansom, Ben Arens, Adin Leibel
Discipline: Medicine

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