Aditya Bade, PhD - Assistant Professor
Research Interests:
Neurodevelopmental Biology, Neurodegenerative Disorders, HIV-1, Anti-Retroviral Therapy (ART), Nanomedicine, Bioimaging, Toxicology, and Biomarker Discovery
Publications
Highlighted Publications:
Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE. Creation of a long-acting nanoformulated dolutegravir. Nat Commun. 2018 Feb 6;9(1):443. PubMed PMID: 29402886; PubMed Central PMCID: PMC5799307.
Gnanadhas DP, Dash PK, Sillman B, Bade AN, Lin Z, Palandri DL, Gautam N, Alnouti Y, Gelbard HA, McMillan J, Mosley RL, Edagwa B, Gendelman HE, Gorantla S. Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs. J Clin Invest. 2017 Mar 1;127(3):857-873. PubMed PMID: 28134625; PubMed Central PMCID: PMC5330738.
Kevadiya BD, Bade AN, Woldstad C, Edagwa BJ, McMillan JM, Sajja BR, Boska MD, Gendelman HE. Development of europium doped core-shell silica cobalt ferrite functionalized nanoparticles for magnetic resonance imaging. Acta Biomater. 2017 Feb;49:507-520. PubMed PMID: 27916740; PubMed Central PMCID: PMC5501313.
Bade AN, Gendelman HE, Boska MD, Liu Y. MEMRI is a biomarker defining nicotine-specific neuronal responses in subregions of the rodent brain. Am J Transl Res. 2017;9(2):601-610. PubMed PMID: 28337287; PubMed Central PMCID: PMC5340694.
Bade AN, Gorantla S, Dash PK, Makarov E, Sajja BR, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y. Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice. Mol Neurobiol. 2016 Jul;53(5):3286-3297. PubMed PMID: 26063593; PubMed Central PMCID: PMC4676748.
Olson KE, Bade AN, Schutt CR, Dong J, Shandler SJ, Boska MD, Mosley RL, Gendelman HE, Liu Y. Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease. Neurotherapeutics. 2016 Jul;13(3):635-46. PubMed PMID: 27329163; PubMed Central PMCID: PMC4965412.
Sajja BR, Bade AN, Zhou B, Uberti MG, Gorantla S, Gendelman HE, Boska MD, Liu Y. Generation and Disease Model Relevance of a Manganese Enhanced Magnetic Resonance Imaging-Based NOD/scid-IL-2Rγc(null) Mouse Brain Atlas. J Neuroimmune Pharmacol. 2016 Mar;11(1):133-41. PubMed PMID: 26556033; PubMed Central PMCID: PMC4871948.
Bade AN, Zhou B, Epstein AA, Gorantla S, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y. Improved visualization of neuronal injury following glial activation by manganese enhanced MRI. J Neuroimmune Pharmacol. 2013 Sep;8(4):1027-36. PubMed PMID: 23729245; PubMed Central PMCID: PMC3746563.