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University of Nebraska Medical Center

Pediatric Cancer

PCRG director, Don Coulter, MD moderates opening remarks at the 2023 PCRG Symposium featuring UNMC Chancellor, Jeffrey Gold, MD; Nebraska Governor Jim Pillen; and Children's Nebraska President and CEO Chanda Chacon

The Pediatric Cancer Research Group (PCRG) is a multidisciplinary team of scientists working to improve the outcomes of children diagnosed with cancer by combining the scientific infrastructure of the UNMC and the Fred & Pamela Buffet Cancer Center with the resources and clinical expertise of Children’s Nebraska.

The PCRG is the pediatric cancer CHRI area of emphasis (AOE), and its efforts span:

  • Epidemiology and prevention, including extensive research into water quality as it relates to pediatric cancer rates in Nebraska and other rural areas
  • Pathology of different cancers/tumors, including medulloblastoma, neuroblastoma, hematological malignancies and more
  • Innovative treatments with collaborators from pharmaceutical sciences and increased infrastructure to conduct clinical trials, including augmenting data management
  • Quality of care research, such as the use of robotics and virtual reality to improve experiences in physical therapy or decrease the need for sedation in radiation oncology and imaging
  • Survivorship research in partnership with Children’s Nebraska Survivorship Clinic
  • Developing resources and tools to benefit a wide range of cancer research, including animal models and tumor banks
  • Training for the next generation of researchers through fellowships and laboratory experiences

If you are a CHRI member and would like to join the Pediatric Cancer area of emphasis, please email chri@unmc.edu

Funding through the PCRG

  • In early 2014, LB 764 was introduced by State Senator Danielle Conrad to appropriate $1.8M from the General Fund for pediatric cancer research infrastructure at the University of Nebraska.
  • In early 2015, LB 417 was introduced by State Senators Nordquist and Mello and subsequently approved to continue appropriations of $1.8M per year (with $300K per year reserved for neuro-oncology) in perpetuity.
  • 2023, Nebraska legislators approve $2.7M a year increase, bringing the yearly state funding for pediatric cancer research to $4.5M.

To ask a question contact: PCRG Program Director, Don Coulter, MD dwcoulter@unmc.edu. Applications are accepted throughout the year. Applicants should be members of CHRI and can access the funding application on the member portal.

Co-Champions

Professor, Division of Pediatric Hematology/Oncology

Don Coulter, MD

Director for Research, Pediatric Critical Care Medicine Associate Professor, Department of Pediatrics Associate Professor, Department of Biochemistry

Sidharth Mahapatra, MD, PhD
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PCRG in the News

PCRG Director, Don Coulter, MD, discusses research through CHRI on the rates of pediatric cancer and pediatric brain tumors in Nebraska.

Collaborative Focus Areas

Within the Pediatric Cancer AOE, two collaborative focus areas have emerged to address specific areas in research. The Nebraska Children’s Brain Tumor Collaborative formed due to connections made at the Pediatric Cancer Research Symposium, and the Hematological Malignancies Subgroup came out of conversations started at Pediatric Cancer AOE events.