UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Targets, Modulators, and Delivery Program

This program is developing and delivering small molecules to modulate validated cancer targets as eventual cancer therapeutics.

The program brings together investigators with complementary expertise to facilitate translation of basic science discoveries across the bench-to-bedside continuum within the research programs of the Eppley Institute and its partner, the Fred & Pamela Buffett Cancer Center. 

Areas of expertise include:

  • Cancer target validation and characterization
  • Medicinal chemistry
  • Pharmacology
  • Nanodelivery

The program has led efforts to establish several shared resources, including the Synthetic and Medicinal Chemistry Resource, the Computational Chemistry Resource, and the Translational Drug Development Resource.

Co-leaders

Paul Trippier, PhD

Professor, UNMC Department of Pharmaceutical Sciences
Co-Director, T32 Training Program in Alzheimer’s Disease and Related Dementias Drug Discovery

402-836-9763
402-559-5673

Paul Trippier

Nicole Shonka, MD

Professor, UNMC Division of Oncology & Hematology
Clinic and Infusion Medical Director, Fred & Pamela Buffett Cancer Center
Neuro Oncology, Sarcoma

Nicole Shonka, MD

Program Members

Jennifer M. Bailey-Lundberg, PhD

Associate Professor, UNMC Department of Pathology, Microbiology and Immunology
Director, Solid Tumor Cancer Immunology Section

402-559-6690

Bailey-Lundberg Lab

Jennifer M. Bailey-Lundberg, PhD

Michael Baine, MD, PhD

Associate Professor, UNMC Department of Radiation Oncology
Clinic Medical Director, Nebraska Medicine

Dr. Michael Baine

Martin Conda-Sheridan, PhD

Associate Professor, UNMC Department of Pharmaceutical Sciences

402-559-9361
402-559-5673

Martin Conda-Sheridan

Don Coulter, MD

Professor, UNMC Division of Hematology/Oncology
Edna Ittner Chair of Pediatric Hematology and Oncology
Director, Pediatric Cancer Research Group

Don Coulter, MD

Christopher R. D'Angelo, MD

Assistant Professor, UNMC Division of Hematology & Oncology
Benign Hematology, Bone Marrow Transplant, Lymphoma, Chronic Lymphocytic Leukemia

Christopher R D’Angelo, MD

Apar Kishor Ganti, MD

Professor, UNMC Division of Oncology & Hematology
Dr. and Mrs. D. Leon UNMC Research Fund Chair in Internal Medicine
Associate Director for Clinical Research, Fred & Pamela Buffett Cancer Center

Apar Ganti, MD
TMDP

Targets, Modulators, and Delivery Member Directory

Find the complete list of Target, Modulators, and Delivery program members in the Member Directory, and learn about their research focus, tools, and techniques that support team science.