Targets, Modulators, and Delivery Program
This program is developing and delivering small molecules to modulate validated cancer targets as eventual cancer therapeutics.
The program brings together investigators with complementary expertise to facilitate translation of basic science discoveries across the bench-to-bedside continuum within the research programs of the Eppley Institute and its partner, the Fred & Pamela Buffett Cancer Center.
Areas of expertise include:
- Cancer target validation and characterization
- Medicinal chemistry
- Pharmacology
- Nanodelivery
The program has led efforts to establish several shared resources, including the Synthetic and Medicinal Chemistry Resource, the Computational Chemistry Resource, and the Translational Drug Development Resource.
Co-leaders
Paul Trippier, PhD
Professor, UNMC Department of Pharmaceutical Sciences
Co-Director, T32 Training Program in Alzheimer’s Disease and Related Dementias Drug Discovery
402-836-9763
402-559-5673

Nicole Shonka, MD
Professor, UNMC Division of Oncology & Hematology
Clinic and Infusion Medical Director, Fred & Pamela Buffett Cancer Center
Neuro Oncology, Sarcoma

Program Members
Jennifer M. Bailey-Lundberg, PhD
Associate Professor, UNMC Department of Pathology, Microbiology and Immunology
Director, Solid Tumor Cancer Immunology Section

Michael Baine, MD, PhD
Associate Professor, UNMC Department of Radiation Oncology
Clinic Medical Director, Nebraska Medicine

Martin Conda-Sheridan, PhD
Associate Professor, UNMC Department of Pharmaceutical Sciences
402-559-9361
402-559-5673

Don Coulter, MD
Professor, UNMC Division of Hematology/Oncology
Edna Ittner Chair of Pediatric Hematology and Oncology
Director, Pediatric Cancer Research Group

Christopher R. D'Angelo, MD
Assistant Professor, UNMC Division of Hematology & Oncology
Benign Hematology, Bone Marrow Transplant, Lymphoma, Chronic Lymphocytic Leukemia

Apar Kishor Ganti, MD
Professor, UNMC Division of Oncology & Hematology
Dr. and Mrs. D. Leon UNMC Research Fund Chair in Internal Medicine
Associate Director for Clinical Research, Fred & Pamela Buffett Cancer Center


Targets, Modulators, and Delivery Member Directory
Find the complete list of Target, Modulators, and Delivery program members in the Member Directory, and learn about their research focus, tools, and techniques that support team science.