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University of Nebraska Medical Center

Pathology Shared Resource

Pathology

As a shared research resource supported by the Fred & Pamela Buffett Cancer Center (FPBCC) the Pathology Tissue Science Facility (TSF) and the Tissue Procurement Shared Resource (TPSR) supports the research community at the UNMC for studies on animal and human tissues. 

Pathology Shared Resource Specific Aims: 

  • Provide comprehensive tissue resources, histology, immunohistochemistry and digital pathology services. 
  • Maximize the effectiveness of our resources by training and mentoring users. 
  • Support long-term sustainability of core services through modernization and innovation. 
  • Provide tissue samples from paraffin, frozen, and autopsy sources 

Equipment: 

  • Ventana Discovery Ultra-IHC  
  • Leica CM1860-Cryostat 
  • Tissue-Tek Prisma/Glas-Automatic stainer/Coverslipper 
  • LeicaAperio CS2-Bright field scanner 

Services: 

  • Comprehensive Histology 
  • Multiplex Immunohistochemistry 
  • Assay Development 
  • Tissue Microarray Construction 
  • Whole Slide Brightfield Digital Imaging 
  • User Support, Training and Equipment 

 

Find more information on services, pricing, and request form.  

Impact

Pathology

The Pathology Shared Resource is located in Durham Research Center I, and the Eppley Cancer Institute, where 80% of FPBCC members are based, provides them with easy access.

The collaboration between the Tissue Science Facility (TSF) and the Tissue Procurement Shared Resource supports clinical and translational research through easy access to flash-frozen tissue samples. The Tissue Procurement Shared Resource (Frozen Bank) consists of flash-frozen tissue from various neoplastic and non-neoplastic diseases. These tissues are obtained from patients who have consented for scientists to use this extra material for research purposes and are not required for diagnosis. 

The Tissue Science Facility (TSF) provides essential services for processing paraffin-embedding, and sectioning collected tissue specimens. The TSF has also been instrumental in sharing specific human frozen liver samples to validate findings from murine studies. 

Co-Directors

Kirk Foster, MD

Co-Director, Pathology Shared Resource, Tissue Science

Benjamin Swanson, MD, PhD

Co-Director, Pathology Shared Resource, Tissue Banking