The Fred & Pamela Buffett Cancer Center

Patient Care
- Research Overview
- - Membership Directory
    Search a listing of full members of the Fred & Pamela Buffett Cancer Center, as well as directories of members by research program.
  - Membership Criteria
    Learn about the criteria for becoming a member of the Fred & Pamela Buffett Cancer Center.
  - Become a Member
    Apply for membership in the Fred & Pamela Buffett Cancer Center by submitting a short form.
- - Shared Resources
    The Fred & Pamela Buffett Cancer Center is home to state-of-the-art facilities and provides support to shared resources at UNMC.
  - UNMC Cores and Shared Resources
    Researchers also have access to shared resources through the UNMC Office of the Vice Chancellor for Research.
  - Request Research Space
    Complete this form to request research space.
- - Cancer Biology Program
    The Fred & Pamela Buffett Cancer Center Cancer Biology Program represents a long-standing commitment to cancer mechanisms-focused research.
  - Targets, Modulators and Delivery Program
    This program develops and delivers small molecules to modulate validated cancer targets as eventual cancer therapeutics.
  - Cancer Prevention & Control Program
    This program aims at identifying and understanding the factors influencing cancer risk, with a special emphasis on disparities and rural populations in the catchment area.
- - Registries
    View registries that are currently enrolling subjects through iCaRe2.
  - Information for Patients
    Participation helps researchers understand specific cancer types, determine risk factors, advance treatment for patients and discover cancer prognostic markers.
  - Information for Researchers
    iCaRe2 aims to foster clinical and epidemiological studies and accelerate the secondary use of cancer and health related data for translational research.
  - Information for Sponsors
    Your gift will support the continuous system growth and improve strides in personalized medicine, diagnosis, treatment and prevention of cancer.
- Community Outreach Overview
- Mission
  The Community Outreach and Engagement Office aims to reduce overall cancer burden and eliminate cancer-related health disparities in its catchment area.
- Community Advisory Board
  This board advises on the direction of cancer center research, dissemination of evidence from ongoing research activities, and policy recommendations.
- Speaker's Bureau
  The Fred & Pamela Buffett Cancer Center Speakers Bureau provides resources to community groups across Nebraska including experts to give presentations on cancer-related topics.
- Resources
  The Community Outreach and Engagement Office provides such resources as videos, infographics, reports and community needs assessments.
- Our Team
  Find members of the Community Outreach and Engagement Office team.
- Nebraska Breast Health Navigation Program
  This program is working to eliminate barriers for breast cancer survivors, using trained volunteers called Lay Patient Navigators who provide peer-to-peer support.
Training & Education
- Leadership Overview
- Director's Message
  Read a message from Joann Sweasy, PhD, director of the Fred & Pamela Buffett Cancer Center.
- About the Center
  Learn about the mission and vision of the Fred & Pamela Buffett Cancer Center.

— The Fred & Pamela Buffett Cancer Center — Research — Shared Resources — Bioinformatics Shared Resource

Bioinformatics Shared Resource

Bioinformatics

The Fred & Pamela Buffett Cancer Center (FPBCC) Bioinformatics Shared Resource fosters research and teaching activities related to bioinformatics and systems biology.

Bioinformatics Shared Resource Specific Aims:

Develop the needed infrastructure to provide up-to-date bioinformatic data analysis services.

Provide expert consultation, access to resources and data analysis services to meet the bioinformatic needs of FPBCC investigators.

Equipment:

Husker HPC Cluster with 6 nodes- 432 Cores, up to 1 TB RAM/node and up to 1 Petabyte storage space

Two GPU Lambda servers with 64 Cores, 16 GPUs and up to 1.5 TB RAM and 24 GB of VRAM/GPU

Five Virtual Machines (VMs) for custom use

Services:

Primary analysis of NGS and multiome datasets (whole genome/exome, transcriptome, epigenome, metagenome, single cell multiome)

Analysis of public domain datasets such as TCGA, ICGC and TARGET, and downstream characterization of genes and gene products

ML/DL/AI applications for cancer subtyping, prognostic prediction, and biomarker identification

Grant support – consultation on experimental design, data access, data deposition, support letters

Find more information on: Services, Pricing and Request Form

Impact

Bioinformatics

The Bioinformatics Shared Resource is located in the Durham Research Center I, allowing 80% of the FPBCC members easy access.

The Bioinformatics Shared Resource is instrumental in offering pilot support for high-performance computing infrastructure, enabling virtual screening of ultra-large compound libraries with local resources.

It has also contributed to the development of several online and cloud-based bioinformatics training modules, as well as ML/AI tools for cancer subtyping.

Director

Babu Guda, PhD

Director, Bioinformatics Shared Resource