Justin Mott, MD, PhD
Justin Mott, MD, PhD, is an associate professor in the Department of Biochemistry and Molecular Biology at the University of Nebraska Medical Center. Dr. Mott heads a research program to use innovative models and techniques for the study of liver cancer. Specifically, research in the Mott lab is focused on cholangiocarcinoma, a biliary tract cancer. He is engaged in medical education and mentoring.
We have learned that science is a team effort and we work to make a laboratory environment that encourages success in and beyond science. This means treating trainees with respect, encouraging outside activities, fostering a creative environment, and building a collaborative team. We have also learned from patients who have been diagnosed with cholangiocarcinoma. Their resilience and willingness to share their experiences and hopes with us motivate our studies.
– Bachelor of Science, Biology and Biochemistry Majors, University of Denver, CO
– PhD, Molecular Microbiology and Immunology, Saint Louis University, MO (2003)
– MD, Saint Louis University, MO (2004)
– Internal Medicine Internship, Mayo Clinic, Rochester, MN
– Postdoctoral Fellow, Mayo Clinic, Rochester, MN
- Co-directs the Gastrointestinal Block for medical students
- Teaches nutrient biochemistry, liver cancer, and DNA & RNA biology for medical students
- Directs the UNMC MD-PhD Scholars Program
- Teaches professional development for MD-PhD Students
- Engages in medical education, recruitment, physician and scientist training, and mentoring
- Facilitates mentorship skills training to promote the conditions needed for learning and provide professional development for faculty and students
- Uses evidence-based mentorship methods and concepts that allow for guiding and advising students
The Mott Laboratory has a healthy environment to pursue science and thrive as a person. On an individual basis, there may be research opportunities available for trainees who are ready to apply innovative approaches to study liver cancer.
- Cholangiocarcinoma (liver cancer)
- Cholangiocyte injury in non-alcoholic steatohepatitis
- MicroRNA expression and function
- Apoptosis resistance mechanisms
- Cholangiocarcinoma cell death mechanisms
- Non-alcoholic fatty liver disease
- MicroRNA Signaling
Current Projects
My lab is focused on cell death in liver cancer, specifically cholangiocarcinoma, a malignant tumor arising in the bile duct epithelium.