Justin Mott, MD, PhD
Dr. Mott heads a research program to use innovative models and techniques for the study of liver cancer. Specifically, research in the Mott lab is focused on cholangiocarcinoma, a biliary tract cancer. He is engaged in medical education, STEM outreach, and mentoring.
We have learned that science is a team effort and we work to make a laboratory environment that encourages success in and beyond science. This means treating trainees with respect, encouraging outside activities, fostering a creative environment, and building a collaborative team. We have also learned from patients who have been diagnosed with cholangiocarcinoma. Their resilience and willingness to share their experiences and hopes with us motivate our studies.
– Bachelor of Science, Biology and Biochemistry Majors, University of Denver, CO
– PhD, Molecular Microbiology and Immunology, Saint Louis University, MO (2003)
– MD, Saint Louis University, MO (2004)
– Internal Medicine Internship, Mayo Clinic, Rochester, MN
– Postdoctoral Fellow, Mayo Clinic, Rochester, MN
– Co-director for the Gastrointestinal Block for medical students
– Teach nutrient biochemistry, liver cancer, and DNA & RNA biology for medical students
– Director of the UNMC MD-PhD Scholars Program
– Teach professional development for MD-PhD Students
– Inclusion, diversity, and equity roles in the Department of Biochemistry and Molecular Biology and the medical curriculum
– Safe Space trained as an ally to lesbian, gay, bisexual, trans spectrum, queer spectrum, intersex, asexual, gender spectrum, Two-Spirit, and sexuality spectrum (LGBTQIA2S+) students, faculty, and staff
Research Opportunities
The Mott Laboratory has a healthy environment to pursue science and thrive as a person. We value inclusion and benefit from new perspectives. On an individual basis, research opportunities are available for students who want to learn and study liver cancer.
Research Interests
- Cholangiocarcinoma (liver cancer)
- Cholangiocyte injury in non-alcoholic steatohepatitis
- MicroRNA expression and function
- Apoptosis resistance mechanisms
Research Projects
- Cholangiocarcinoma cell death mechanisms
- Non-alcoholic fatty liver disease
- MicroRNA Signaling
Current Projects
My lab is focused on cell death in liver cancer, specifically cholangiocarcinoma, a malignant tumor arising in the bile duct epithelium.