Darlene Veruttipong

Colorectal Cancer in Gharbiah, Egypt

AUTHORS: Darlene Veruttipong, LS Rozek, A Hablas, IA Seifeldin, M Ramadan, AS Soliman

BACKGROUND:
Colorectal Cancer is the third most common cancer worldwide. When compared with other Middle East Cancer Consortium (MECC) countries and the US SEER population, Egypt has the lowest age standardized rates (ASR) for ages 50 years and older, but one of the highest ASR for those under 40 years old. The purpose of this study is to describe the distribution of colorectal cancer with respect to age and urban-rural status in Gharbiah, Egypt between 1999 and 2007 by age, stage, grade, polyp status, topology and histology.

METHODS:
Age, residence, diagnosis date, grade, stage, topology, and histology variables from colorectal cancer cases diagnosed from 1999 to 2007 were collected from the Gharbiah population-based cancer registry. The Egyptian census was used to provide population counts by age, urbanization, and district. Results: Descriptive statistics were analyzed on 1269 cases of colorectal cancer from 1999-2007. 56.7% of cancers were situated in the colon, whereas 43.3% were in the rectum. Very few cases had polyps (3.1%) and 27.3% had mucinous tumors. There was a higher frequency of polyps (3.7%) in the urban population, but the rural population had slightly more mucinous tumors (32.5%). Overall, the urban population has a higher age standardized rate (ASR), however there is a slow increase in rural ASR. Gharbiah has a higher age specific incidence rate (ASIR) than the US SEER for those younger than 30 years, but much lower rate for those over 40 years from 2000 to 2007.

CONCLUSIONS:
Gharbiah has unique characteristics and distribution of colorectal cancer. This distribution differs from the US SEER and the variation also occurs within the urban rural populations. Further comparisons may lead to a novel understanding of the colorectal cancer etiology in Egypt.

About Darlene
Darlene Veruttipong is originally from Los Angeles, California and frequently travels to Thailand to visit her extended family. She graduated from University of California, San Diego with a bachelors in microbiology and a minor in healthcare social issues. After graduation, Darlene worked at Cedar-Sinai Medical Center in rheumatologic research and volunteered in Huehuetenango, Guatemala before continuing her education in public health. She graduated from University of Michigan School of Public Health in April 2011 with an MPH in Epidemiology and an interdepartmental concentration on global health.
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