College of Medicine

- Admissions Overview
- - MD Program
    UNMC's rigorous academics, diverse clinical experiences and supportive environment put you on the path to becoming a skilled, compassionate physician.
  - How to Apply
    UNMC prepares medical degree students to meet the needs of patients through clinical practice, biomedical science and research, problem-solving and compassion.
  - Contact Us
    Review contact information for the Office of Admissions and Student Affairs in the College of Medicine at UNMC.
  - Verification and State Licensure
    Review opportunities for state licensure following completion of the MD program in the College of Medicine at UNMC.
- - MD-MBA Program
    A combined MD-MBA degree equips you with the tools you need to become highly skilled in both management and medicine.
  - MD-MPH Program
    Pursue your passion for public health and medicine with a combined MD-MPH and help solve complex health problems.
  - MD-PhD Program
    Do you have a passion for caring for patients and for research? Consider the dual MD-PhD degree.
- Education Overview
- - Curriculum
    Our curriculum produces physicians whose foundation in basic, clinical, and health systems sciences prepare them to promote health and reduce patient suffering.
  - Graduation Requirements
    Review requirements for students pursuing an MD at the UNMC College of Medicine to graduate and receive their degree.
  - Objectives
    The objectives of UNMC's medical degree program are to prepare you for success in primary care or specialty fields.
  - Service Learning
    Active participation in community service provides critical opportunities to apply skills and knowledge gained in medical school and develop a sense of empathy.
- - Enhanced Medical Education
    Enhanced Medical Education Tracks offer medical students an opportunity to perform an in-depth study of an interdisciplinary field of medicine.
  - Enhanced Medical Education Tracks
    EMET applicants are selected for Tracks based on their interest in the topic and motivation to complete work above and beyond the primary MD curriculum.
  - MD Honor’s Thesis Program
    The MD honors thesis encourages students to engage in scientific research during medical education and become eligible to graduate with honors.
- Research Overview
- Internal Grants
  The College of Medicine has a variety of research-related grant and award opportunities available to UNMC faculty.
- Comparative Effectiveness Research
  The Comparative Effectiveness Research (CER) program identifies knowledge gaps in the effectiveness of clinical care and improves CER in these areas.
- Great Plains IDeA-CTR
  The Great Plains IDeA-CTR is a collaborative effort between nine regional institutions that provides training, resources. and funding to regional researchers.
- Research and Development Committee
  The Research and Development Committee handles funding opportunities for faculty, including the Bridge Funding program, and student research opportunities.
- Student Opportunities
  The College of Medicine provides a variety of research opportunities for both current and prospective UNMC students.
- Residencies & Fellowships Overview
- Graduate Medical Education Programs
  UNMC's dozens of programs--including nearly 20 in internal medicine--allow residents and fellows a variety of specialties.
- House Officer Resources
  Find information for residents and fellows, including salaries, benefits and nearby housing.
- House Officer Wellness
  Wellness resources for residents and fellows include an assistance program and a private wellness lounge.
- Research
  We aim to facilitate house officers’ involvement in research in the areas of patient safety, quality improvement, healthcare disparities and education research.
- Salary and Benefits
  Paid vacation and professional leave, health insurance and meal allowances are just a few of the benefits residents receive in addition to their yearly salary.
- Contact Us
  Reach out to the Graduate Medical Education office for information about benefits, contracts, orientation or graduation.
Departments

— College of Medicine — Department of Pharmacology and Experimental Neuroscience — Research — Core Facilities — Elutriation

Elutriation

The Elutriation Core Facility in the Department of Pharmacology and Experimental Neuroscience provides state-of-the art isolation of monocytes and lymphocytes from peripheral blood mononuclear cells (PBMCs). These mononuclear phagocytes play a very important role in neurodegenerative disorders such as HIV/AIDS and AIDS dementia, Alzheimer’s diseases, Parkinson’s disease, and Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig’s Disease) and therefore are critical tools allowing researchers and scientists to actively study the many aspects of these diseases.

Elutriation is a gentle process known as counter-current centrifugal elutriation. In this process, the PBMCs are placed into a specially designed centrifuge rotor/chamber and subjected to centrifugal field. The cells are then sequentially washed out of the rotor based on their size, using a buffer stream that flows in the direction opposite the centrifugal field. By balancing centrifugal force against the opposing buffer flow, lymphocytes, which are about 6-8 mm and monocytes, which are 8-10 µm, will be selectively removed from the mixture.

Elutriation is processed every Tuesday and takes approximately seven hours to complete and yield >97% purity of monocytes and lymphocytes. Cells are generally available around 4:00 p.m. Request for cells should be done Friday before the week of elutriation and/or by prior arrangement with Myhanh Che (402) 559-5981.

Elutriated cell requester must have approved IRB and approval from Dr. Howard E. Gendelman, Core Facility Director and Department Chair.
Freshly obtained elutriated cells should be cultured soon after receipt of cells and no later than 24 hours.
Primary human cells come from healthy donors should be treated as infectious and handled using universal safety precautions. Review universal precautions at the Centers for Disease Control and Prevention.

User fees are set to share the cost associated with this core facility.

Contacts

To order cells and for more information, contact Myhanh Che (phone: 402-559-5981).

Interested in becoming our donor? Please contact Theresa Grutel (phone: 402-559-5478).

Donor is compensated as allowed by the IRB.